Author Reply to “Is Criticism About Inherent Biases in Rigorous Orthopaedic Trials Prone to Biases?”
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Revealing biases inherent in recombination protocols
BACKGROUND The recombination of homologous genes is an effective protein engineering tool to evolve proteins. DNA shuffling by gene fragmentation and reassembly has dominated the literature since its first publication, but this fragmentation-based method is labor intensive. Recently, a fragmentation-free PCR based protocol has been published, termed recombination-dependent PCR, which is easy to...
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A considerable literature now shows that perceived criticism (PC) predicts clinical outcomes transdiagnostically. Recent work has begun to identify potential mechanisms underlying PC’s connection to clinical outcomes. For example, anomalies have been found in neural processing when individuals who rate their key relatives as highly critical listen to criticism. To explore whether high-PC indivi...
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Illusory correlation experiments indicate that people overestimate the association between random presentations of snake slides and shock, but do not overestimate the association between random presentations of slides of damaged and exposed electric outlets (DEEOs) and shock. To investigate whether reports of covariation biases might be attributable to expectancy biases, we had Ss rate the a pr...
متن کاملBiases in clinical trials with sequential monitoring
Objectives It is well known that a sequentially monitored clinical trial that stops early for benefit has a crude treatment difference that overestimates the true treatment effect. This has led to extended debate in the literature, with some researchers arguing that early stopping is an important source of bias in meta-analyses of clinical trials. We therefore investigated the implications of e...
متن کاملComparing jumping to conclusion and personalization biases in schizophrenic patients with and without medication therapy
Introduction: Previous studies have reported contradicting results about the effect of medication therapy on attribution bias and jumping to conclusion (JTC) bias in schizophrenic patients. This study aims at analyzing the effect of medication on attribution bias and JTC bias in schizophrenic patients. Methods: This study is an ex post facto and casual-comparative research. 28 people includi...
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ژورنال
عنوان ژورنال: Arthroscopy: The Journal of Arthroscopic & Related Surgery
سال: 2021
ISSN: 0749-8063
DOI: 10.1016/j.arthro.2020.11.002